干细胞注射可以抗衰老吗? Can stem cells be anti - aging?

2016/04/29

  一.干细胞注射抗衰老有没有依据

  答:常见的可能是间充质干细胞(MSC),至少从目前来看还是有点靠谱的。

  间充质干细胞在体内或体外特定的诱导条件下,可以分化成多种组织细胞,连续传代培养和冷冻保存后仍具有多向分化潜能,可作为理想的种子细胞用于衰老和病变引起的组织器官损伤修复。

  所以抗衰老不过是利用了间充质干细胞的多能性,并不针对于皮肤啥的,对一些如肝硬化之类的疾病也有作用。我认识的做这个的人,自己用这个把自己的肝硬化治好了。

  之所以这个常见,是因为这种干细胞基本没有免疫原性;输的量和浓度不能太大,一般需要稀释,过量的副作用基本类似于输血。本身不是突变的体细胞,直接致癌作用和自体细胞差别不大(具体和癌症的关系我就不了解了)。

  这是一种你自己本身就有的东西,实际上相当于小幅度加强该功能。

  二. 怎么保证干细胞在人体自动分化需要的细胞?

  答:没办法保证。

  无奈的是,现在的生物技术水平根本做不到对人体内的细胞分化进行操控。

  但是,但是,但是,人体的复杂程度远超一般人的想象,主要有两点对这项技术有帮助:

  1.归巢潜能

  归巢是指是指髓系细胞向特定组织汇集的现象,像T细胞前体汇聚到胸腺,就是从骨髓中分化到一定程度,由于表面受体特异性前往需要他们的地方的现象,不知道说明白没……

  间充质干细胞也有归巢潜能,会主动汇集到需要他们的地方。

  2.分化调节

  由于各种激素/信号之间的微妙差异,使我们身体的细胞自觉地从干细胞分化成血细胞、肝细胞、脑细胞等等。上一步归巢的间充质干细胞,他归巢到需要他的地方后,会和该区域的其他干细胞受到相同的诱导条件,进而会分化为相同的细胞。

  所以间充质干细胞一般会自动跑到需要他们的地方,自动分化成需要的细胞,不需要人工干预。像来了一群盟友新兵,司令部没办法挨个调度他们,交给前线指挥官就好了。

A. Have stem cell injections of anti-aging

 

A: common ectomesenchymal stem cells (MSC), may be at least for the moment I still have a ones.

 

Mesenchymal stem cells in vivo or in vitro induced specific conditions, can differentiate into a variety of tissue cells, continuous subculture and still have after cryopreservation multi-directional differentiation potential, can be used as ideal seed cells used for tissue damage caused by aging and disease.

 

So anti-aging is use the pluripotency of mesenchymal stem cells, not against the skin, also has effect for some disease such as cirrhosis of the liver. Do I know this person, oneself use the cured his cirrhosis of the liver.

 

The common, because this kind of stem cells in the basic no immunogenicity; Lose the quantity and the concentration of cannot too big, generally need to dilute, the side effects of excessive basic similar to blood transfusion. Itself is not a somatic mutation, carcinogenesis and directly from somatic cell difference (concrete relationship with cancer I don’t know).

 

This is a kind of your own itself some things, effectively strengthen the function of small amplitude.

 

2. How to guarantee the automatic differentiation of stem cells in the human body needs of the cell?

 

A: can’t guarantee.

 

Helpless, biological technology today simply can’t do to control the cell differentiation in the human body.

 

But, but, but, the complexity of the human body than most people imagine, there are two main are helpful to the technology:

 

1. The homing potential

 

Homing refers to refers to the phenomenon of myeloid cells to specific tissues together, like a t-cell precursors converge to the thymus, is the differentiation from bone marrow, where they are needed because the surface receptor specificity to the phenomenon, don’t know understand not to say…

 

Mesenchymal stem cells have potential of homing, takes initiative to wherever they are needed.

 

2. Differentiation regulation

 

Due to the subtle differences between various hormones/signal, consciously make our body’s cells from stem cells into blood cells, liver cells, brain cells, and so on. Between the step on the homing of mesenchymal stem cells, after homing to the need of his place, he will be in the region and the other stem cells induced by the same conditions, who will be divided into the same cell.

 

Ectomesenchymal stem cells, so usually will automatically run to wherever they are needed, automatically need to differentiate into cells, without human intervention. Like to recruit a group of Allies, command can’t dispatch them, each one handed over to the front commander.